Geert Bultynck Selected Research

ML 9

10/2022

The alkalinizing, lysosomotropic agent ML-9 induces a pH-dependent depletion of ER Ca2+ stores in cellulo.

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Geert Bultynck Research Topics

Disease

40	Neoplasms (Cancer) 03/2024 - 08/2007
9	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 03/2024 - 06/2017
6	Starvation 12/2018 - 12/2011
5	B-Cell Lymphoma (Lymphoma, B Cell) 01/2022 - 07/2015
5	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2021 - 03/2011
5	Ischemia 01/2019 - 08/2012
3	Necrosis 10/2018 - 05/2011
2	Parkinson Disease (Parkinson's Disease) 01/2023 - 01/2020
2	Prostatic Neoplasms (Prostate Cancer) 10/2022 - 04/2015
2	Muscular Diseases (Myopathy) 10/2022 - 04/2011
2	Fibrosis (Cirrhosis) 01/2022 - 01/2019
2	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 01/2013
2	Carcinogenesis 01/2020 - 06/2016
2	Reperfusion Injury 01/2019 - 01/2013
2	Hypoxia (Hypoxemia) 01/2019 - 08/2012
2	Pancreatitis 10/2018 - 01/2018
2	Carcinoma (Carcinomatosis) 06/2017 - 08/2013
2	Lymphoma (Lymphomas) 03/2011 - 07/2004
2	Autosomal Dominant Polycystic Kidney (ADPKD) 11/2010 - 06/2010
1	Heart Diseases (Heart Disease) 01/2023
1	Crohn Disease (Crohn's Disease) 01/2023
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2022
1	Cardiac Arrhythmias (Arrythmia) 01/2022
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2022
1	Hypertrophy 01/2022
1	Wolfram Syndrome (Syndrome, Wolfram) 09/2021
1	Inborn Genetic Diseases (Disease, Hereditary) 09/2021
1	Heart Failure 01/2021
1	Multiple Myeloma 01/2020
1	Kidney Diseases (Kidney Disease) 01/2020
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Wounds and Injuries (Trauma) 01/2019
1	Autoimmune Diseases (Autoimmune Disease) 11/2018
1	Nervous System Diseases (Neurological Disorders) 11/2018
1	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 01/2018
1	Cystinosis 10/2016
1	Bone Diseases (Bone Disease) 01/2016
1	Breast Neoplasms (Breast Cancer) 01/2016
1	Neoplasm Metastasis (Metastasis) 01/2016
1	Inflammation (Inflammations) 01/2015

Drug/Important Bio-Agent (IBA)

21	Proteins (Proteins, Gene)FDA Link 09/2021 - 04/2011
10	Connexin 43 (Connexin43)IBA 01/2021 - 11/2010
9	Peptides (Polypeptides)IBA 01/2021 - 11/2010
7	venetoclaxIBA 01/2023 - 08/2016
7	CalciumIBA 10/2022 - 08/2007
6	Inositol 1,4,5-Trisphosphate Receptors (Inositol Triphosphate Receptor)IBA 01/2021 - 04/2015
4	Inositol 1,4,5-TrisphosphateIBA 01/2020 - 06/2017
3	Apoptosis Regulatory ProteinsIBA 01/2022 - 09/2015
3	Adenosine Triphosphate (ATP)IBA 10/2018 - 01/2013
3	Sirolimus (Rapamycin)FDA Link 01/2018 - 01/2017
2	Phosphotransferases (Kinase)IBA 01/2023 - 01/2017
2	ConnexinsIBA 01/2023 - 01/2016
2	ActomyosinIBA 01/2020 - 11/2010
2	Beclin-1IBA 06/2016 - 12/2011
1	1,2- bis(2- aminophenoxy)ethane- N,N,N',N'- tetraacetic acid (BAPTA)IBA 01/2023
1	S63845IBA 01/2023
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2023
1	Leucine (L-Leucine)FDA Link 01/2023
1	ML 9IBA 10/2022
1	Mitochondrial Permeability Transition PoreIBA 10/2022
1	Myosin-Light-Chain KinaseIBA 10/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	IronIBA 09/2021
1	SulfurIBA 09/2021
1	Ru265IBA 01/2021
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2021
1	Amino Acids FDA Link 01/2021
1	Apolipoprotein L1IBA 01/2020
1	BDA-366IBA 01/2020
1	AcidsIBA 01/2019
1	CollagenIBA 01/2019
1	Transcription Factors (Transcription Factor)IBA 01/2019
1	Protein Isoforms (Isoforms)IBA 11/2018
1	Enzyme Precursors (Zymogens)IBA 10/2018
1	Inositol 1,4,5-trisphosphate 3-kinaseIBA 01/2018
1	Taurolithocholic AcidIBA 01/2018
1	TOR Serine-Threonine KinasesIBA 01/2018
1	Bile Acids and Salts (Bile Acids)IBA 01/2018
1	EnzymesIBA 01/2018
1	taurolithocholic acid 3-sulfate (TLC-S)IBA 01/2018
1	Bcl-2-Like Protein 11IBA 12/2017
1	DPB162-AEIBA 06/2017
1	IonsIBA 01/2017
1	NucleosidesIBA 01/2017
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2017
1	Cystine (L-Cystine)IBA 10/2016
1	SaltsIBA 01/2016
1	SolutionsIBA 01/2016
1	NucleotidesIBA 01/2016
1	bafilomycin A1IBA 01/2016
1	Diphosphonates (Bisphosphonates)IBA 01/2016
1	Testosterone (Sustanon)FDA Link 04/2015
1	AndrogensIBA 04/2015
1	Hormones (Hormone)IBA 04/2015

Therapy/Procedure

12	Therapeutics 03/2024 - 10/2014
1	Immunotherapy 01/2020
1	Carbohydrate Loading Diet 10/2018
1	Drug Therapy (Chemotherapy) 01/2018
1	Radiotherapy 06/2017